Little Whistle, a real guinea pig who lives in a store called Toytown, helps his toy friends write a letter to Santa asking if he made them.

Stink Moody, friends Webster and Sophie, and Mrs. Birdwistle visit tourist attractions in Virginia as they try to give away 101 guinea pigs rescued from a laboratory, although Stink is very reluctant to relinquish his favorite, Astro.

Jack Frost steals Georgia the Guinea Pig Fairy's pet and Rachel and Kirsty set out to rescue him.

After winning the lead role in a play, acing a spelling test, and finding money, second-grader Ellie wonders if the Critter Club animal shelter's newest animal--a little pink pig--is bringing her good luck.

While his human Elliot adjusts to his new home and stepfamily, Gizmo, an evil genius guinea pig, searches for a new evil lair where he can plot to take over the world, but Gizmo is constantly thwarted by Elliot's little stepsister Jasmine (who likes to play dress-up), Abuela (who may or may not like to eat cavies), and Wedgie (a Corgi superhero and Gizmo's nemesis).

Lola brings the class guinea pig home for school vacation and when he escapes Charlie tries to help her find him before anything happens to him and before Lola has to go back to school.

As Christmas nears, Amy and her friends in the Critter Club try to find a home for two adorable guinea pigs.

Poppleton the pig makes a new friend after an icicle accident, creates a bust of Cherry Sue, and gets a wintry birthday surprise from his pals.

As Pig tries to write a book, he chastises the reader who keeps interrupting him by turning the pages.

Poppleton the pig enjoys the company of geese flying south, buys a new winter coat with the help of his friend Cherry Sue, and tries to order pancakes at the Lion's Club breakfast.