Flint Minett has keratoconus, an eye disease, but desperately wants to win a comic book art contest so that he and his new friend McKell Panganiban will be better accepted at middle school.

Buzz creates a comic book that features Buzz Boy and Fly Guy as the superheroes.

A fifteen-year-old "geek" who keeps a list of the high school jocks and others who torment him, and pours his energy into creating a great graphic novel, encounters Kyra, Goth Girl, who helps change his outlook on almost everything, including himself.

In trouble with their principal because of their comic books, George and Harold decide to create a new epic novel.

When Harold and George turn fourth-grade teacher Ms. Ribble into an evil monster called the Wedgie Woman, she wreaks havoc on the world, giving the wedgie of doom to unsuspecting people who stand in her way--including principal-turned-superhero Captain Underpants.

Questioning his resolve to attend public school after being homeschooled when he is targeted by a bully, Max aspires to become like his favorite comic book heroes and finds an unexpected opportunity to be the hero his middle school needs.

Thirteen-year-old Dan blames himself when his best friend Nate is hit in the head by a baseball during practice--desperate to help, Dan seizes on the suggestion that even in a coma Nate may be able to hear him, and sets out to read to Nate from the superhero comic books that both boys love.

Michael Malone is assigned to investigate a local comic shop by the mysterious UNICORNE agency because they are displaying a comic book with a disturbingly familiar heroine--but he soon realizes that the sinister shop hides an invisible army come to life, with a menacing maniac at it's head, and worse he does not know if he can trust his fellow agents.

While sitting in detention, George and Harold accidentally create an army of evil talking toilets, and Principal Krupp's alter ego, Captain Underpants, has to save the world from it.

"Li'l Petey, Flippy, and Molly introduce twenty-one rambunctious, funny, and talented baby frogs to the art of comic making. As the story unwinds with mishaps and hilarity, readers get to see the progress, mistakes, and improvements that come with practice and persistence"--